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R&D Pipeline News Vol. 2, Issue 15: Small interfering RNA (siRNA or RNAi) |
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25 Apr 2006 |
Read the highlights of the most recent edition of our weekly R&D information product R&D Pipeline News. The Special Product or Technology Pipelines of R&D Pipeline News are available via subscription of R&D Pipeline News or as a single Project Pipeline List .
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Featured Target Pipeline
Featured Technology Pipeline
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Vol. 2 Issue nº 15
April 24, 2006
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Featured Target Pipeline
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Beta-amyloid antibodies
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- Elan & Wyeth lead the field with phase II antibody;
- Six antibody projects in various stages of development;
- Various antibody technologies used (humanized, fully human, fragments);
- Different molecular targets in beta-amyloid used
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Featured Technology Pipeline
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Small interfering RNA (siRNA or RNAi)
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- Lead project of siRNA technology in phase II for AMD;
- Stability problems solved;
- Topical administration used for early projects;
- Drug delivery technologies enable systemic administration;
- Most frequent use in infectious diseases;
- Technological solution for otherwise non-drugable targets;
- No safety issues so far;
- Few companies share intellectual property position;
- Increasing number of collaborations with Big Pharma partners
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R&D Pipeline News
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R&D Pipeline News is a premier information source about research and development (R&D) projects in the pipeline of the biopharmaceutical industry and is directed to all stakeholders in R&D . R&D Pipeline News covers all relevant treatment modalities, including. drugs, medical devices, biomaterials, combination products, cell therapy and drug delivery products.
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