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R&D Pipeline News Vol. 2, Issue 11: inclu. Anti-CD20 Antibody Pipeline |
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21 Mar 2006 |
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Special Pipeline
Special Company Pipelines
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Vol. 2 Issue nº 11 March 20, 2006
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Special Pipeline
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1. Anti-CD20 Antibody Pipeline
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- Several generations of anti-CD20 murine, chimeric, humanized, human antibodies and derivatives;
- New generations of anti-CD20 preferrably in development for rheumatoid arthritis;
- close competition field of anti-CD20 antibodies in phase II for rheumatoid arthritis;
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Special Company Pipelines
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1. Genentech’s Development Pipeline
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- Massive development program for Avastin line extensions;
- Life cycle management for marketed products dominates clinical pipeline;
- Focus on oncology and immunology
- Mainly biologics in clinical pipeline,
- Four different clinical stage projects in rheumatoid arthritis
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2. Zealand Pharma (Denmark)
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- Specialized on peptide drugs;
- Successful in licensing-out,
- New peptide against chemotherapy-induced diarrhea soon to enter phase I
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3. UCB (Belgium)
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- Anti-epileptic drug Keppra most successful product with rich line extension program;
- Two follow-up projects for Keppra in phase II;
- Celltech projects fill the pipeline;
- Anti-TNF CIMZIA file submitted in US and soon in Europe
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