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Proof of Concept Study in Second Species Demonstrates Increase in Absorption of Oral B12 Using Emisphere Technology Print E-mail
16 Apr 2008

Emisphere Technologies announced today that additional preclinical in vivo studies using dogs further demonstrate that its proprietary eligen(R) technology enhances the absorption of oral B12

CEDAR KNOLLS, N.J., USA | April 16, 2008 | Emisphere Technologies, Inc. (Nasdaq: EMIS) announced today that additional preclinical in vivo studies using dogs further demonstrate that its proprietary eligen(R) technology enhances the absorption of oral B12. These data confirm in a second species Emisphere's earlier-reported proof of concept studies conducted in rats.

"These additional animal studies are an important milestone in our plans to commercialize our eligen(R) technology," said Michael V. Novinski, President and Chief Executive Officer of Emisphere. "Developing a B12 formulation with greater bioavailability will alleviate a significant unmet medical need."

There are currently some five million people in the United States receiving 40 million B12 injections annually to treat a variety of debilitating medical conditions; at least an additional five million people are consuming over 600 million tablets of B12 of various strengths annually.

ABOUT EMISPHERE TECHNOLOGIES, INC.

Emisphere Technologies, Inc. is a biopharmaceutical company that focuses on a unique and improved delivery of therapeutic molecules and pharmaceutical compounds using its eligen(R) Technology. These molecules and compounds could be currently available or are in preclinical or clinical development. Such molecules or compounds usually cannot be delivered by the oral route of administration or the benefits of these compounds are limited due to poor bioavailability, slow on-set of action or variable absorption. The eligen(R) Technology can be applied to the oral route of administration as well other delivery pathways, such as buccal, per rectum, pulmonary, intra-vaginal or transdermal. The web site is: www.emisphere.com.


SOURCE: Emisphere Technologies, Inc.





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