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Pfizer and Scil Finalize Agreement for Novel Cartilage Growth Factor Print E-mail
16 Jan 2008

Pfizer Inc and Scil Technology GmbH have signed a licensing agreement for worldwide collaboration on Scil’s cartilage specific growth factor CD-RAP



NEW YORK & MARTINSRIED, Germany | January 16, 2008 |
Pfizer Inc (NYSE:PFE) and Scil Technology GmbH (Scil) have signed a licensing agreement for worldwide collaboration on Scil’s cartilage specific growth factor CD-RAP. Under this agreement, Pfizer will obtain a worldwide exclusive license to develop and commercialize CD-RAP. In addition to receiving royalties on the sale of any products that may be commercialised under this agreement, Scil is eligible for upfront and milestone payments of approximately U.S. $250 million depending on the achievement of various development and regulatory milestones.

“The successful conclusion of this license agreement with Pfizer increases the company’s value”, stated Dr. Weishui Weiser, managing director of Scil. “In addition, this is one more step towards achieving Scil’s mission, improving the quality of patients’ lives.”

“We are pleased”, added Dr. Volker Lang, vice president, Corporate Development of Scil. ”We believe that having Pfizer as a partner advances Scil as an organisation capable of generating commercial value from scientific expertise.”

“This partnership reflects Pfizer’s ongoing commitment to pursue the best science anywhere on the globe and secure novel technologies and products that will complement our existing research programs,” said Dr. Edmund Harrigan, senior vice president Worldwide Business Development. “We look forward to working with Scil on this collaboration and leveraging our combined resources to develop valuable new treatment options for patients with osteoarthritis.”

About Pfizer

Pfizer discovers and develops innovative medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality healthcare and health system support.

About Scil Technology GmbH

Scil Technology is a privately financed biopharmaceutical development company focused on dental and orthopedic tissue regeneration with a particular emphasis on bone and cartilage repair. The company’s therapeutic candidates are based on recombinant human growth factors. These factors are combined with biodegradable biomaterials to generate local application forms. Scil Technology’s pipeline for dentistry includes products that are targeted at periodontal disease, dental implantology and maxillofacial surgery. Orthopedic products are developed for treatment of traumatic lesions of bone and cartilage and osteoarthritis. Scil Technology is located in the biotechnology cluster in Martinsried, Germany.

For more information on Pfizer or Scil Technology, please visit www.pfizer.com or http://www.sciltechnology.com.

Notes to Editor:

CD-RAP is a polypeptide that has been shown to play a crucial role during cartilage formation during embryonic development and in the matrix stimulation of chondrocytes in adult animals. Furthermore it has been shown to stimulate cartilage synthesis in in-vitro studies with chondrocytes obtained from patients suffering from osteoarthritis. These properties make rhCD-RAP a highly promising candidate for cartilage regeneration in indications such as chondral defects and osteoarthritis.

SOURCE: PFIZER





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