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Small Molecules
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Date Item Title
22 May 2006 Diovan® the first blood pressure medication in a large-scale clinical trial to lower C-reactive protein, an important marker of inflammation
22 May 2006 Researchers Report Results for 28-day Phase II Study of VX-950 in Combination with Pegylated Interferon and Ribavirin in Hepatitis C Patients
22 May 2006 ViroPharma Announces Presentation of HCV-796 Phase 1b Data at Digestive Disease Week
22 May 2006 New Study Demonstrates That AMITIZA(TM) (lubiprostone) May Help Improve Symptoms of Irritable Bowel Syndrome With Constipation
20 May 2006 Synthetic Blood Reaches First Half of Traumatic Brain Injury Trial
19 May 2006 Arena Pharmaceuticals Announces Achievement of Phase 2 Clinical Milestone Under Cardiovascular Disease Collaboration With Merck
19 May 2006 Bristol-Myers Squibb Announces Discontinuation of Development of Muraglitazar, an Investigational Oral Treatment for Type 2 Diabetes
18 May 2006 deCODE Initiates Phase III Trial for DG031 for the Prevention of Heart Attack
18 May 2006 Teva Announces FDA Grants Approval of Azilect® (Rasagiline) for Parkinson's Disease
18 May 2006 Amarin Acquires Parkinson's Disease Drug Candidate
18 May 2006 Independent Data Monitoring Board Recommends Expedited Interim Analysis of Overall Survival Data for Satraplatin Phase 3 Trial
17 May 2006 Carna Biosciences and Enamine Sign Collaboration
17 May 2006 Arginox Pharmaceuticals Reaches 50 Percent Enrollment Target in Its Pivotal Phase 3 Study of Tilarginine Acetate Injection in Cardiogenic Shock
17 May 2006 Rigel Announces Pfizer Selection of R343, a Syk Kinase Inhibitor, for Advanced Preclinical Development in Allergic Asthma
17 May 2006 Targacept Announces Positive Phase II Results for TC-1734 (AZD3480) in Memory Impaired Older Subjects
17 May 2006 Vertex Pharmaceuticals Initiates Phase I Development for VX-770 in Cystic Fibrosis
17 May 2006 Phase III Community-Acquired Pneumonia Study Opens for Basilea’s Novel Broad-spectrum anti-MRSA Antibiotic Ceftobiprole to Broaden Indications
17 May 2006 New data demonstrates efficacy of Rasilez as a potentially innovative oral direct renin inhibitor for treatment of high blood pressure
17 May 2006 Novartis announces first Phase III Exforge data, shows strong efficacy as new high blood pressure treatment with dual mechanisms of action
17 May 2006 Basilea Completes Patient Recruitment of Alitretinoin Pivotal Phase III Study in Patients with Severe Chronic Hand Dermatitis
17 May 2006 NicOx and Ferrer Select Candidate for Development In Dermatology Collaboration
17 May 2006 Valeant Receives FDA Marketing Approval for Cannabinoid Cesamet(TM) (CII)
17 May 2006 ABILIFY(R) (Aripiprazole) Demonstrated Efficacy as Maintenance Therapy In Adults with Bipolar I Disorder Following Treatment for a Recent Manic or Mixed Episode
17 May 2006 MIGENIX Receives Approval for MX-3253 Phase II Combination Viral Kinetics Study in HCV Treatment-Naive Patients
17 May 2006 Theravance Announces Enrollment of Last Patient in Phase 3 Complicated Skin and Skin Structure Infections Clinical Program with Investigational Antibiotic, Telavancin
17 May 2006 Neurocrine Receives Approvable Letter for indiplon Capsules and Non-Approvable for indiplon Tablets for the Treatment of Insomnia
17 May 2006 Nymox Reports Positive New Efficacy Data for Benign Prostatic Hyperplasia Drug
17 May 2006 Manhattan Pharmaceuticals Receives SwissMedic's Approval To Commence Phase IIa Trial With OE, Its Oral Obesity Drug Candidate
17 May 2006 Marshall Edwards achieves special protocol assessment and agreement with the FDA
17 May 2006 PhytoMedical’s BDC-O3 Compound Shown to Elevate HDL, “Good” Cholesterol
16 May 2006 Hedgehog Antagonist Data Presented at Australasian College of Dermatologists Scientific Meeting
16 May 2006 GlaxoSmithKline and Vertex Pharmaceuticals Announce Preliminary 48-Week Results from Head-to-Head Clinical Study of HIV Protease Inhibitors Lexiva (Telzir) and Kaletra in Treatment-naïve Patients with HIV
16 May 2006 GPC Biotech Announces Start of Phase 1 Trial Evaluating Satraplatin plus Xeloda® in Patients with Advanced Solid Tumors
16 May 2006 BioAlliance Pharma Starts Pivotal Phase III Clinical Trial in the US of Loramyc(R) Treatment for Oropharyngeal Candidiasis
16 May 2006 U.S. FDA Grants Orphan Drug Designation to OXiGENE's Lead Clinical Candidate, Combretastatin A4P (CA4P), for the Treatment of Ovarian Cancer; Award Marks Second Orphan Drug Indication for CA4P
16 May 2006 Eisai Files Application with the MHRA for New Aricept(R) Indication: Severe Alzheimer's Disease
16 May 2006 Pixantrone Produces High Rate (77 percent) of Complete Tumor Disappearance in Patients with Relapsed Indolent Non-Hodgkin's Lymphoma
16 May 2006 Taro to Begin Dose Escalation Study of T2000 in Canada to Evaluate Efficacy in Essential Tremor
16 May 2006 European Commission Approves Keppra(R) for Use as Adjunctive Therapy in the Treatment of Myoclonic Seizures in Patients with Juvenile Myoclonic Epilepsy
16 May 2006 TorreyPines Therapeutics Completes Phase I Clinical Trial for Tezampanel (NGX424), a First-in-Class Compound for Acute Migraine
16 May 2006 Axonyx Announces Completion Of The Multiple-Dose Phase I Study Of Posiphen
15 May 2006 New Prescription Pain Treatment Completes European Mutual Recognition Procedure
15 May 2006 Sosei Discontinues Development Of SOU-001
15 May 2006 Advancis Pharmaceutical Receives FDA Approval Letter for New Strengths of Keflex
15 May 2006 EntreMed Initiates Combination Phase 2 Clinical Trial With Panzem(R) NCD in Carcinoid Cancer
15 May 2006 Geron And TA Therapeutics Announce Presentation Of New Data Supporting Utility Of Their Small Molecule Telomerase Activator TAT0002
15 May 2006 Nereus Pharmaceuticals Initiates Phase I Clinical Trial for Anti-Cancer Proteasome Inhibitor
15 May 2006 GTx, Inc. Initiates Phase II Clinical Trial of Ostarine, a First-in-Class Drug
13 May 2006 PTC Therapeutics Initiates Phase 1a Clinical Trial of PTC299
12 May 2006 Pfizer's Smoking Cessation Medicine Chantix™ (Varenicline) Receives FDA Approval
 
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