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Small Molecules
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Date Item Title
14 Aug 2008 Abbott and AstraZeneca expand relationship to include co-promotion of CRESTOR(R)
13 Aug 2008 Diakron Licenses Anticoagulant Drug Candidate from Merck & Co., Inc. Orchid Pharma partners with Diakron
13 Aug 2008 Lexicon Pharmaceuticals Identifies New Drug Candidate for Glaucoma
12 Aug 2008 Threshold Pharmaceuticals Initiates a Second Clinical Trial Evaluating TH-302 in Patients With Solid Tumors
12 Aug 2008 U.S. Food and Drug Administration Approves Viread(R) for Chronic Hepatitis B in Adults
12 Aug 2008 FDA Accepts REMOXY New Drug Application and Grants Priority Review
12 Aug 2008 Oxygen Biotherapeutics Develops Gel Version of Oxycyte(R) for Treating Surface Wounds
12 Aug 2008 Bronchinol Cystic Fibrosis Dose Trial Results Positive
12 Aug 2008 PolyMedix Has Regulatory Clearance to Initiate Phase I Clinical Study of Novel Anticoagulant Antagonist Compound
12 Aug 2008 Algeta begins first US clinical trial of Alpharadin in men with advanced prostate cancer
12 Aug 2008 EPIX Pharmaceuticals Initiates Phase 2b Right-Heart Catheterization Study of PRX-08066 in Patients with Chronic Obstructive Pulmonary Disease and Moderate-to-Severe Pulmonary Hypertension
12 Aug 2008 Cell Therapeutics Announces that the European Organization for Research and Treatment of Cancer Completes Enrollment in Phase II Clinical Trial of Brostallicin as First Line Therapy for Advanced or Metastatic Soft Tissue Sarcoma
11 Aug 2008 Cardiome and Astellas Announce Receipt of FDA Approvable Letter for KYNAPID
11 Aug 2008 DiaMedica Enrolls First Patient in Phase IIa Clinical Trial for DM-99
11 Aug 2008 WILEX starts patient recruitment in Phase II breast cancer trial with its uPA inhibitor MESUPRON(R) (WX-671)
11 Aug 2008 Enrollment in Phase IIb Clinical Trial for I-vation(TM) TA (MK-0140) Suspended Pending Review of Study Design by Merck & Co., Inc.
11 Aug 2008 Human rhinovirus Phase IIa clinical trial commences
10 Aug 2008 FDA Allows Phase 2 Study for Sound Pharmaceuticals' Novel Drug to Prevent Chemotherapy Induced Hearing Loss
10 Aug 2008 Multaq(R) (dronedarone) Granted FDA Priority Review for Patients with Atrial Fibrillation
10 Aug 2008 Ardea Biosciences Presents Phase 2a Antiviral Activity Data for Lead HIV Candidate, RDEA806 at XVII International AIDS Conference
07 Aug 2008 ProteoTech's Exebryl-1(R) Enters Human Clinical Trials for the Treatment of Alzheimer's Disease
07 Aug 2008 IMPAX Reports Positive Results in Phase III Trial with IPX056
07 Aug 2008 Sonus Pharmaceuticals Signs Exclusive In-Licensing Agreement With Bayer Healthcare for Caspase Activator Compounds
07 Aug 2008 GPC Biotech Reports that Celgene to Terminate Co-Development and License Agreement for Satraplatin
07 Aug 2008 Ore Pharmaceuticals Acquires Rights to Develop a Second Drug Candidate from Roche
07 Aug 2008 Lipitor 80 mg Reduced the Risk of Heart Attack and Stroke in Patients with Heart Disease, Type 2 Diabetes and Chronic Kidney Disease
07 Aug 2008 Head-to-Head 96-Week Study Shows EPZICOM(R) is Comparable to Truvada(R) in Efficacy and Safety Measures in HIV Treatment-Naive Patients
06 Aug 2008 Xanodyne Pharmaceuticals, Inc. Achieves Positive Efficacy Results in Pivotal Phase 3 Studies of Proprietary Modified Release Oral Tranexamic Acid Product Candidate for Heavy Menstrual Bleeding
06 Aug 2008 Ninety-Six Week Data on Tibotec Investigational NNRTI, TMC278, Presented at AIDS 2008
06 Aug 2008 ARIAD Announces Start of Phase 2 Clinical Study of Oral Deforolimus in Patients with Advanced Endometrial Cancer
06 Aug 2008 Inhibitex Reports Initiation of Multiple Ascending Dose Trial of FV-100 for Shingles
06 Aug 2008 Cortex's AMPAKINE Molecule CX717 Has Positive Effects in Opiate-Induced Respiratory Depression in a Phase IIa Clinical Study
05 Aug 2008 The Medicines Company's Cleviprex(TM) Receives FDA Approval
05 Aug 2008 Infinity Highlights Clinical Advances in Its Portfolio of Anti-Chaperone Agents and Announces Second Quarter Financial Results
05 Aug 2008 Pharmasset Reports Preliminary Results of a 4-week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
05 Aug 2008 Hollis-Eden Pharmaceuticals Commences Phase I/II Clinical Trial with TRIOLEX(TM) (HE3286) in Rheumatoid Arthritis Patients
05 Aug 2008 CASTLE Data Showed Boosted REYATAZ(R) (atazanavir sulfate) and Lopinavir/r Achieved Similar Results for Undetectable Viral Load in Treatment-Naive HIV-1 Infected Patients, Regardless of Gender
05 Aug 2008 ISENTRESS(R) (raltegravir), Merck's First in Class Integrase Inhibitor, Reduced HIV Viral Load and Increased CD4 Cell Counts Through 96 Weeks in Treatment-Naïve HIV-Infected Patients When Taken With Other Anti-HIV Medicines
05 Aug 2008 Cara Therapeutics Announces Successful Completion of Phase I Clinical Trial of Novel Analgesic, CR845
05 Aug 2008 Icon Bioscience Completes Enrollment in Phase I Study of Novel Ophthalmic Drug Candidate
04 Aug 2008 Tracleer(R) (bosentan) receives EU approval for treatment of patients with mildly symptomatic Pulmonary Arterial Hypertension
04 Aug 2008 Single-pill combinations Diovan HCT(R) and Exforge(R) approved in US as first-line treatments for high blood pressure
04 Aug 2008 Karo Bio Announces Successful Phase II Study with Eprotirome in Combination with Statin
04 Aug 2008 Alkermes Announces Approval of VIVITROL(R) for the Treatment of Alcohol Dependence in Russia
04 Aug 2008 Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients
04 Aug 2008 Theratechnologies Reports on Positive Body Image Parameters at the International AIDS Conference
04 Aug 2008 New data shows HIV therapy tipranavir (Aptivus(R)) is effective and well tolerated in children
04 Aug 2008 Amicus Therapeutics Announces Successful Completion of End of Phase 2 Meeting With FDA for Amigal in Fabry Disease
03 Aug 2008 U.S. FDA Issues Action Letter for Sugammadex
03 Aug 2008 Evotec Announces Initiation of Phase I Clinical Trial of VR1 Antagonist under Partnership with Pfizer Inc.
 
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