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Small Molecules
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Date Item Title
17 Nov 2008 Freedom-C Trial of Oral Treprostinil in Pulmonary Arterial Hypertension Fails to Meet Primary Endpoint
17 Nov 2008 Solvay Pharmaceuticals discontinues R&D activities of its anti-obesity compound SLV319
17 Nov 2008 First pivotal trials begin for Boehringer Ingelheim’s novel triple angiokinase inhibitor Vargatef(TM) (BIBF 1120)
17 Nov 2008 ARYx Therapeutics Presents Clinical Data for ATI-5923 at American Heart Association Scientific Sessions 2008
17 Nov 2008 Debiopharm and Pharmaleads sign license agreement for Debio 0827 or PL37 in treatment of chronic pain conditions
17 Nov 2008 FDA Approves BANZEL(TM) (rufinamide)
17 Nov 2008 Start of Phase III Trial on the Anti-influenza Drug CS-8958
17 Nov 2008 Alkermes Presents Positive Preclinical Data on Novel, Proprietary Molecule Designed to Improve Outcomes for Patients Taking Opioid Analgesics
17 Nov 2008 ZIOPHARM Oncology Presents Positive Data from Studies of Palifosfamide
17 Nov 2008 Lilly Licenses U.S. Rights for Tadalafil PAH Indication to United Therapeutics
17 Nov 2008 Cenomed BioSciences Presents Data on New Drug Candidates at the Society for Neuroscience in Washington DC
13 Nov 2008 Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Successfully Completes Phase 1 Clinical Trials
13 Nov 2008 SEROQUEL XR and SEROQUEL Approved in Europe for New Indications for the Treatment of Bipolar Disorder
13 Nov 2008 Actelion's first-in-class selective S1P1 receptor agonist to enter Phase II clinical development
13 Nov 2008 Chelsea Therapeutics Initiates Phase I Clinical Trial of CH-4051
13 Nov 2008 ISTA Pharmaceuticals Files New Drug Application with U.S. FDA for Bepreve(TM)
13 Nov 2008 Last patient treated in the extension phase of the confirmatory study testing tesamorelin in HIV-associated lipodystrophy
13 Nov 2008 Genetic Immunity(R) Announces First Patient Dosed In Phase II Trial With DermaVir Patch For HIV Disease
12 Nov 2008 Longest follow-up period for any new oral anticoagulant explores Pradaxa(R) (dabigatran etexilate) for stroke prevention in atrial fibrillation (AF)
12 Nov 2008 Transdermal Diclofenac enters Phase 1 Clinical Trial in Humans
12 Nov 2008 Metabolex Announces Positive Results From Phase 1a Clinical Trial of MBX-2982
12 Nov 2008 Tibotec Data Presented at ICAAC and HIV9 Follow key Regulatory Approvals for Anti-HIV Compounds
12 Nov 2008 Optimer Pharmaceuticals Reports Positive Data from its North American Phase 3 CDI Study of OPT-80
12 Nov 2008 Novexel’s NXL104/ceftazidime Combination Commences Phase II Clinical Trial in Hospital Patients with complicated Urinary Tract Infections
11 Nov 2008 Rasilez(R), first-in-class direct renin inhibitor, provides greater reduction in high blood pressure than ACE inhibitor ramipril in patients 65 and older
11 Nov 2008 Anesiva Announces Adlea ACTIVE-1 Phase 3 Clinical Results, Ceasing of Zingo Commercial Operations and Restructuring
11 Nov 2008 Anthera's Varespladib Demonstrates Significant Anti-Inflammatory Effect and LDL Reduction in Patients with Coronary Heart disease
11 Nov 2008 Cell Therapeutics' Pixantrone Phase III (EXTEND) Pivotal Trial Successful in Achieving Primary Endpoint
11 Nov 2008 RVX-208 Data Demonstrates Increase in Functional HDL Particles
11 Nov 2008 Raptor Pharmaceuticals Corp. Announces Positive Phase IIa Clinical Study Results for Convivia(TM) Program
11 Nov 2008 Rigel's R788 Phase 2a Results Published in Arthritis and Rheumatism
11 Nov 2008 INNO-406 Demonstrates Positive Clinical Responses in Phase 1 Trial in Patients with Chronic Myeloid Leukemia
11 Nov 2008 Alba Therapeutics Announces Enrollment of Its First European Patient in Global Phase IIb Study of Larazotide Acetate for Treatment of Active Celiac Disease
10 Nov 2008 Lorus Successfully Completes IND-Enabling Toxicology Studies for Lead Small Molecule Anticancer Drug LOR-253
10 Nov 2008 Rivaroxaban Phase II Dose-Ranging Study Demonstrates Encouraging Response Rates in Treatment of Acute Coronary Syndrome Patients
10 Nov 2008 GSK and XenoPort Announce Plans to Withdraw and Resubmit New Drug Application Requesting Approval of Solzira(TM) for Restless Legs Syndrome
10 Nov 2008 ArQule and Daiichi-Sankyo Enter Into Strategic R&D Partnership to Progress Novel Compounds to Target Cancer
10 Nov 2008 Roche, InterMune and Pharmasset Announce Initiation of INFORM-1, the First Dual-Combination Clinical Trial with Oral Antivirals in Hepatitis C
10 Nov 2008 Potentia Pharmaceuticals' Drug Candidate for Age-Related Macular Degeneration Shows Positive Safety Profile in Phase I Clinical Trial
10 Nov 2008 Results of Studies of ALVESCO(R) for the Treatment of Asthma and OMNARIS(TM) in an HFA Nasal Aerosol Presented at American College of Allergy, Asthma & Immunology Annual Meeting
10 Nov 2008 EyeGate Pharma Enrolls First Dry Eye Patient in Phase II Clinical Trial of Lead Product EGP-437
10 Nov 2008 Gene Signal Enters Phase III Clinical Tests for the Prevention of Corneal Graft Rejection
10 Nov 2008 RVX-208 Exploratory Study Illustrates Early Potential for Alzheimer's Disease
10 Nov 2008 EntreMed’s MKC-1 Meets Primary Efficacy Endpoint in Non-Small Cell Lung Cancer Clinical Trial
10 Nov 2008 VIA Pharmaceuticals Announces Positive Results of Phase 2 Studies of VIA-2291 in Patients With Serious Cardiovascular Disease
10 Nov 2008 FibroGen Announces New Research on HIF-PHI and Anti-CTGF Development Programs in Chronic Kidney Disease
09 Nov 2008 CRESTOR Demonstrates Dramatic CV Risk Reduction in a Large Statin Outcomes Study
07 Nov 2008 Tarceva brings new hope to patients with advanced non-small cell lung cancer
07 Nov 2008 Santhera Presents Preclinical Data on Oral MC4 ReceptorAntagonists for Treatment of Cancer Cachexia at AICR Research Conference
07 Nov 2008 Theratechnologies presents additional results from its tesamorelin Phase 3 studies at the 10th International workshop on adverse drug reactions and lipodystrophy in HIV
 
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