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DNA, RNA & Cells
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Date Item Title
04 Jun 2008 Newly Published Study Shows OPKO's siRNA Bevasiranib Is Taken Up by Target Tissues in the Eye
04 Jun 2008 Nuvelo Initiates Phase 1B Clinical Trial of Anticoagulant NU172
03 Jun 2008 Isis' Partners Present Clinical Data on Antisense Drugs at the American Society of Clinical Oncology
03 Jun 2008 EMEA provides Guidance on Phase III Design and Approval Requirements
03 Jun 2008 Anti-TGF-beta Antisense AP 12009 shows very good Safety and Tolerability in Systemic Treatment of Pancreatic Carcinoma, Malignant Melanoma and Colorectal Carcinoma
03 Jun 2008 Oncogenex reports that low serum clusterin levels were predictive of survival in preliminary analyses of phase 2 study of lead drug candidate OGX-011
03 Jun 2008 Calando Pharmaceuticals Doses First Patient in siRNA Phase I Clinical Trial
02 Jun 2008 Biovex reports positive phase II clinical trial results of Oncovexgm-CSF in metastatic melanoma at the 2008 American Society of Clinical Oncology Meeting
30 May 2008 BioAlliance Pharma Presents New Results on its AMEP(TM) anti-invasive biotherapy
30 May 2008 VIRxSYS Presents New VRX496 Phase II HIV Gene Therapy Trial Data
30 May 2008 AMT Announces Positive Interim Clinical Data on its Lead Product AMT-011
30 May 2008 Genasense(R) Chemotherapy Program Yields High Response Rate in Patients with Stage 4 Melanoma
30 May 2008 Targeted Genetics Reports Additional Data From Inflammatory Arthritis Clinical Trial
29 May 2008 Phase I/II Study of Targeted Gene Delivery In Vivo - Intravenous Infusions of REXIN-G - Demonstrates Dose-Dependent Anti-Tumor Activity Without Toxicity in Patients With Progressive Chemo-Resistant Bone and Soft Tissue Sarcoma (ASCO 2008)
28 May 2008 Santaris Pharma begins human clinical testing of the world’s first medicine targeted at a human microRNA
28 May 2008 ADVEXIN(R) Improves Survival in Recurrent, Refractory Head and Neck Cancer Patients
27 May 2008 Alnylam and Takeda Form Strategic Worldwide Platform Alliance in RNAi TherapeuticsAlnylam and Takeda Form Strategic Worldwide Platform Alliance in RNAi Therapeutics
21 May 2008 Cell Genesys Reports Encouraging Interim Data From Phase 1 Clinical Trial of CG0070 in Recurrent Bladder Cancer
19 May 2008 Preclinical Data Demonstrate Ability to Regenerate an Entire Bladder with Tengion Neo-Bladder Replacement(TM)
16 May 2008 OncoGenex reports updated survival data on OGX-011 in a second-line chemotherapy trial for patients with prostate cancer
15 May 2008 FDA Places Geron’s GRNOPC1 IND on Clinical Hold
13 May 2008 AVI BioPharma Announces Significant Advance in the Potential Treatment of Ebola and Marburg Virus Infections
12 May 2008 Argos Therapeutics Initiates Phase 2 Proof-of-Concept Trial for its Arcelis(TM) Personalized Immunotherapy Platform in HIV
09 May 2008 Oncolytics Biotech Inc. Starts Patient Enrolment in U.K. Combination REOLYSIN(R)/Cyclophosphamide Trial
09 May 2008 Osiris and NuVasive Enter into Definitive Agreement for Osteocel(R)
08 May 2008 Osiris Receives Approval for Use of Prochymal(TM) Under FDA Expanded Access Treatment Program
07 May 2008 FDA and the Paul Ehrlich Institute (Germany) Approve Pluristem’s Regulatory Submissions in Support of a Phase I/II Clinical Trial Utilizing PLX-PAD for Peripheral Artery Disease
05 May 2008 MOLOGEN AG receives approval for clinical study with cancer drug MGN1703
02 May 2008 Celgene Cellular Therapeutics Announces Clinical Transplant of Human Placenta-Derived Stem Cells
30 Apr 2008 Topigen reports progess toward clinical trials for TPI 1100 at Rnai World CongressTopigen reports progess toward clinical trials for TPI 1100 at Rnai World Congress
29 Apr 2008 Nuvelo Announces Positive Proof-of-Concept Data With Anticogulant NU172
28 Apr 2008 Targeted Genetics Announces Data From First Gene Therapy Trial for Leber's Congenital Amaurosis in New England Journal of Medicine
28 Apr 2008 Alnylam and Collaborators at MIT Publish Research on the Discovery of 'Lipidoids', a Novel Class of Lipid-Based Molecules for the Delivery of RNAi Therapeutics
25 Apr 2008 FDA Provides Clarity to Isis Regarding the Development Path for Mipomersen
23 Apr 2008 ReNeuron announces further pre-clinical data with its ReN003 programme for diseases of the retina
22 Apr 2008 Lorus initiates development program exploring novel route of administration for LOR-2040
21 Apr 2008 Calando Receives FDA Approval for Phase I Clinical Trial Using a Targeted siRNA Nanoparticle Therapeutic
18 Apr 2008 Isis Reports Reduction of apoB-100 Levels in a Murine Model Resulting in Up to 92% Reduction of Atherosclerosis
17 Apr 2008 GlaxoSmithKline and Regulus Therapeutics form strategic alliance to develop microRNA targeted therapeutics to treat inflammatory diseases
16 Apr 2008 Aldagen Announces Initiation of ALD-101 Phase III Trial for Improving Cord Blood Transplants in Pediatric Patients With Inherited Metabolic Diseases
16 Apr 2008 Lorus Therapeutics presents new findings for the anticancer drugs LOR-253 and LOR-2040
14 Apr 2008 Cephalon Announces European Commission Approval of EFFENTORA for the Treatment of Breakthrough Cancer Pain
09 Apr 2008 Alnylam Initiates Phase II Trial to Evaluate Safety and Tolerability of ALN-RSV01 in Adult Lung Transplant Patients Naturally Infected with Respiratory Syncytial Virus (RSV) Infection
08 Apr 2008 Bristol-Myers Squibb Selects Isis Drug Targeting PCSK9 as Development Candidate for Prevention and Treatment of Cardiovascular Disease
07 Apr 2008 Targeted Genetics Acquires Rights to siRNA Development Program in Huntington's Disease From Sirna Therapeutics
07 Apr 2008 Danish biotech company's restorative Alzheimer's product has successfully been implanted in patients
01 Apr 2008 Amorcyte Completes Phase I Trial of Stem Cell Therapy for Acute Myocardial Infarction
01 Apr 2008 Final Data From the Bioheart Seismic Trial Suggest Safety, Efficacy of Autologous Stem-Cell Therapy for Treating Congestive Heart Failure
31 Mar 2008 Argos Therapeutics Presents Positive Phase 1 Safety Data for its Arcelis Platform in HIV at Keystone Symposia
31 Mar 2008 Alnylam Presents Pre-clinical Data from Hypercholesterolemia, Liver Cancer, Ebola, and Progressive Multifocal Leukoencephalopathy (PML) Programs at RNAi Keystone Symposium
 
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